The thing I love about my job as a lab technician is that there is always so much to learn…
After spending time working in the highly interesting world of cancer research and in dental regenerative field, I am back to my first love: the intriguing world of cardiac ion channels! Trying to understand their precise localization in various cell types, finding their binding partners, understanding how mutation linked to various diseases affect them and may affect their localization/stability/structure is a constant rewarding challenge!
The thing I love about my job as a lab technician is that there is always so much to learn: new techniques but also always new projects to work on, new collaborations. I particularly enjoy teaching students, you constantly meet new people from all around the world and all this together makes you grow all the time. There is never a boring routine!
When not in the lab, I love crafting, hiking, or going for a treasure hunt in the forest with my family and reading, reading and reading!
On the Web
Institute of Biochemistry and Molecular Medicine
⃰ All these papers were published under my maiden name: Zmoos Anne-Flore.
Hubner EK, Lechler C, Kohnke-Ertel B, Zmoos AF, Sage J, Schmid RM, Ehmer U. An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes. J Gene Med. 2017 Jan;19(1-2). doi: 10.1002/jgm.2940.
Xu L, Hazard FK, Zmoos AF, Jahchan N, Chaib H, Garfin PM, Rangaswami A, Snyder MP, Sage J. Genomic analysis of fibrolamellar hepatocellular carcinoma. Hum Mol Genet. 2015 Jan 1;24(1):50-63. doi: 10.1093/hmg/ddu418.
Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O’Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, Brunet A, Sage J, Wernig M. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 2015 Jan 8;16(1):39-50. doi: 10.1016/j.stem.2014.10.019.
Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J. Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Cell Rep. 2014 Jul 24;8(2):371-81. doi: 10.1016/j.celrep.2014.06.025.
Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S, Albesa M, Bittihn P, Luther S, Lehnart SE, Hatem SN, Coulombe A, Abriel H SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. Circ Res. 2011. Feb4;108(3):294304. doi: 10.1161/CIRCRESAHA.110.228312.