Please find below a list of our most recent (2020-2024) original articles. More articles are on EuroPMC, click here.

  1. Iamshanova O, Hämmerli AF, Ramaye E, Seljmani A, Ross-Kaschitza D, Schärz N, Essers M, Guichard S, Rougier JS, Abriel H. The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5. PLoS One. 2024;19:e0298820. doi: 10.1371/journal.pone.0298820
  2. Selimi Z, Rougier JS, Abriel H, Kucera JP. A detailed analysis of single-channel Na(v) 1.5 recordings does not reveal any cooperative gating. J Physiol. 2023;601:3847-3868. doi: 10.1113/jp284861
  3. Boukenna M, Rougier JS, Aghagolzadeh P, Pradervand S, Guichard S, Hämmerli AF, Pedrazzini T, Abriel H. Multiomics uncover the proinflammatory role of Trpm4 deletion after myocardial infarction in mice. Am J Physiol Heart Circ Physiol. 2023;324:H504-h518. doi: 10.1152/ajpheart.00671.2022
  4. Arullampalam P, Essers MC, Boukenna M, Guichard S, Rougier JS, Abriel H. Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiol Rep. 2023;11:e15783. doi: 10.14814/phy2.15783
  5. Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, Abriel H. Deletion of Trpm4 Alters the Function of the Na(v)1.5 Channel in Murine Cardiac Myocytes. Int J Mol Sci. 2021;22. doi: 10.3390/ijms22073401
  6. Hu Y, Kaschitza DR, Essers M, Arullampalam P, Fujita T, Abriel H, Inoue R. Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflugers Arch. 2021;473:507-519. doi: 10.1007/s00424-020-02507-w
  7. Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, Abriel H. Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Front Pharmacol. 2021;12:712354. doi: 10.3389/fphar.2021.712354
  8. Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na(v)1.5. Channels (Austin). 2020;14:268-286. doi: 10.1080/19336950.2020.1805999
  9. Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H. Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circ Arrhythm Electrophysiol. 2020;13:e008241. doi: 10.1161/circep.119.008241
  10. Amarouch MY, Kurt H, Delemotte L, Abriel H. Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na(v)1.5. Molecules. 2020;25. doi: 10.3390/molecules25040902