Please find below a list of our most recent (2018-2023) original articles. More articles are on EuroPMC, click here.

  1. Selimi Z, Rougier JS, Abriel H, and Kucera JP. A detailed analysis of single-channel Na(v) 1.5 recordings does not reveal any cooperative gating. J Physiol 2023.
  2. Boukenna M, Rougier JS, Aghagolzadeh P, Pradervand S, Guichard S, Hämmerli AF, Pedrazzini T, and Abriel H. Multiomics uncover the proinflammatory role of Trpm4 deletion after myocardial infarction in mice. Am J Physiol Heart Circ Physiol 324: H504-h518, 2023.
  3. Dokshokova L, Franzoso M, Di Bona A, Moro N, Sanchez Alonso JL, Prando V, Sandre M, Basso C, Faggian G, Abriel H, Marin O, Gorelik J, Zaglia T, and Mongillo M. Nerve growth factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. J Physiol 600: 2853-2875, 2022.
  4. Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, and Abriel H. Deletion of Trpm4 Alters the Function of the Na(v)1.5 Channel in Murine Cardiac Myocytes. Int J Mol Sci 22: 2021.
  5. Hu Y, Kaschitza DR, Essers M, Arullampalam P, Fujita T, Abriel H, and Inoue R. Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflugers Arch 473: 507-519, 2021.
  6. Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, and Abriel H. Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Front Pharmacol 12: 712354, 2021.
  7. Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, and Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na(v)1.5. Channels (Austin) 14: 268-286, 2020.
  8. Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, and Abriel H. Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circ Arrhythm Electrophysiol 13: e008241, 2020.
  9. Amarouch MY, Kurt H, Delemotte L, and Abriel H. Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na(v)1.5. Molecules 25: 2020.
  10. Vermij SH, Abriel H, and Kucera JP. Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules. Front Physiol 10: 1487, 2019.
  11. Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, and Abriel H. A Distinct Pool of Na(v)1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Front Physiol 10: 834, 2019.
  12. Neubauer J, Wang Z, Rougier JS, Abriel H, Rieubland C, Bartholdi D, Haas C, and Medeiros-Domingo A. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. Int J Legal Med 133: 1733-1742, 2019.
  13. Gillet L, Guichard S, Essers MC, Rougier JS, and Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific reports 9: 19422, 2019.
  14. Delalande C, Awale M, Rubin M, Probst D, Ozhathil LC, Gertsch J, Abriel H, and Reymond JL. Optimizing TRPM4 inhibitors in the MHFP6 chemical space. Eur J Med Chem 166: 167-177, 2019.
  15. Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, and Remme CA. Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. Int J Mol Sci 20: 2019.
  16. Tamò L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, and Geiser T. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American journal of physiology Lung cellular and molecular physiology 315: L921-l932, 2018.
  17. Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J, Lochner M, Peinelt C, Reymond JL, and Abriel H. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. Br J Pharmacol 175: 2504-2519, 2018.
  18. Neubauer J, Rougier JS, Abriel H, and Haas C. Functional implications of a rare variant in the sodium channel β1B subunit (SCN1B) in a 5-month-old male sudden infant death syndrome case. HeartRhythm Case Rep 4: 187-190, 2018.
  19. Hichri E, Abriel H, and Kucera JP. Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc. J Physiol 596: 563-589, 2018.
  20. Chevalier M, Vermij SH, Wyler K, Gillet L, Keller I, and Abriel H. Transcriptomic analyses of murine ventricular cardiomyocytes. Sci Data 5: 180170, 2018.
  21. Bianchi B, Smith PA, and Abriel H. The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Mol Brain 11: 41, 2018