We will see where the wind will push me...
What I like in my professional life is the fact that every day is different. The way in which I have to organize my work, adapt to the experiment or the result, make every day special. It is always a thrilling time when I am about to reveal an unexpected result. I cherish the challenge as I face a problem and the following satisfaction when I can resolve it. Most of all, I take pleasure in the fact that I need some time to reconsider my point and that nothing can be taken for granted.
On the Web
Institute of Biochemistry and Molecular Medicine
Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Gillet L, Guichard S, Essers MC, Rougier JS, Abriel H. Sci Rep. 2019 Dec 19;9(1):19422. doi: 10.1038/s41598-019-55950-w. PMID: 31857666 Free PMC article.
A Distinct Pool of Nav1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, Abriel H. Front Physiol. 2019 Jul 3;10:834. doi: 10.3389/fphys.2019.00834. eCollection 2019. PMID: 31333492 Free PMC article.
An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation. Blancard M, Debbiche A, Kato K, Cardin C, Sabrina G, Gandjbakhch E, Probst V, Haissaguerre M, Extramiana F, Hocini M, Olivier G, Leenhardt A, Guicheney P, Rougier JS. Sci Rep. 2018 Oct 2;8(1):14619. doi: 10.1038/s41598-018-32867-4.PMID:30279520
Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers. Martins M, McCarthy A, Baxendale R, Guichard S, Magno L, Kessaris N, El-Bahrawy M, Yu P, Katan M. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4239-44. doi: 10.1073/pnas.1311500111. Epub 2014 Mar 3. PMID:24591640
Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis. Peschard P, McCarthy A, Leblanc-Dominguez V, Yeo M, Guichard S, Stamp G, Marshall CJ. Curr Biol. 2012 Nov 6;22(21):2063-8. doi: 10.1016/j.cub.2012.09.013. Epub 2012 Oct 11. PMID:23063435